Gstm1^tm1Gcw
Targeted Allele Detail

Summary

• Symbol: Gstm1^tm1Gcw
• Name: glutathione S-transferase, mu 1; targeted mutation 1, George C Wagner
• MGI ID: MGI:4456470
• Gene: Gstm1 Location: Chr3:107919571-107925289 bp, - strand Genetic Position: Chr3, 46.83 cM, cytoband F3
• Alliance: Gstm1^tm1Gcw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159701
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (129S/SvEv x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1 through 5 were replaced with a floxed neo cassette. (J:159701)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gstm1 Mutation: 25 strains or lines available

References

• Original: J:159701 Yochum CL, et al., Animal model of autism using GSTM1 knockout mice and early post-natal sodium valproate treatment. Behav Brain Res. 2010 Jul 11;210(2):202-10
• All: 1 reference(s)