Pate4^tm1(KOMP)Mbp
Targeted Allele Detail

Summary

• Symbol: Pate4^tm1(KOMP)Mbp
• Name: prostate and testis expressed 4; targeted mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:4456499
• Gene: Pate4 Location: Chr9:35518387-35523164 bp, - strand Genetic Position: Chr9, 20.34 cM, cytoband A5.3
• Alliance: Pate4^tm1(KOMP)Mbp page
• IMPC: Pate4 gene page

Mutation origin

• Mutant Cell Lines: DEPD00502_6_A05, DEPD00502_6_A08, DEPD00502_6_B07, DEPD00502_6_B08, DEPD00502_6_D05, DEPD00502_6_D06, DEPD00502_6_D07, DEPD00502_6_D08, DEPD00502_6_E05, DEPD00502_6_E06, DEPD00502_6_E07, DEPD00502_6_E08, DEPD00502_6_F05, DEPD00502_6_F06, DEPD00502_6_F07, DEPD00502_6_F08, DEPD00502_6_G05, DEPD00502_6_G06, DEPD00502_6_G07, DEPD00502_6_G08, DEPD00502_6_H05, DEPD00502_6_H06
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 146 starting at position 35519501 and ending at position 35519647 of Chromosome 9 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Pate4 Mutation: 24 strains or lines available

References

• Original: J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010
• All: 3 reference(s)