Lcp1^tm1Erjb
Targeted Allele Detail

Summary

• Symbol: Lcp1^tm1Erjb
• Name: lymphocyte cytosolic protein 1; targeted mutation 1, Eric J Brown
• MGI ID: MGI:4457016
• Synonyms: LPL^-
• Gene: Lcp1 Location: Chr14:75368570-75468282 bp, + strand Genetic Position: Chr14, 39.63 cM
• Alliance: Lcp1^tm1Erjb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161042
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on polymorphonuclear neutrophil extracts. (J:161042)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcp1 Mutation: 38 strains or lines available

References

• Original: J:161042 Chen H, et al., Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading. Immunity. 2003 Jul;19(1):95-104
• All: 12 reference(s)