Myb^tm2.1Epr
Targeted Allele Detail

Summary

• Symbol: Myb^tm2.1Epr
• Name: myeloblastosis oncogene; targeted mutation 2.1, E Premkumar Reddy
• MGI ID: MGI:4457084
• Synonyms: myb^f
• Gene: Myb Location: Chr10:21000834-21036883 bp, - strand Genetic Position: Chr10, 9.75 cM
• Alliance: Myb^tm2.1Epr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160189
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A floxed neo cassette was inserted upstream of exon 9A and an additional loxP site was inserted downstream of exon 9A. Cre mediated recombination removed the neo cassette leaving exon 9A floxed. (J:160189)

Generation of the Myb^tm2.1Epr and Myb^tm2.2Epr alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myb Mutation: 53 strains or lines available

References

• Original: J:160189 Baker SJ, et al., p89c-Myb is not required for fetal or adult hematopoiesis. Genesis. 2010 May;48(5):309-16
• All: 1 reference(s)