Myb^tm2.2Epr
Targeted Allele Detail

Summary

• Symbol: Myb^tm2.2Epr
• Name: myeloblastosis oncogene; targeted mutation 2.2, E Premkumar Reddy
• MGI ID: MGI:4457094
• Synonyms: c-myb^delta, p89^-
• Gene: Myb Location: Chr10:21000834-21036883 bp, - strand Genetic Position: Chr10, 9.75 cM
• Alliance: Myb^tm2.2Epr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160189
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Modified isoform(s)) Mutations: Insertion, Intragenic deletion Mutation details: Cre mediated recombination removed exon 9A. The absence of p89 protein expression was confirmed by western blot analysis on thymocyte extracts. (J:160189)

Generation of the Myb^tm2.1Epr and Myb^tm2.2Epr alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myb Mutation: 53 strains or lines available

References

• Original: J:160189 Baker SJ, et al., p89c-Myb is not required for fetal or adult hematopoiesis. Genesis. 2010 May;48(5):309-16
• All: 1 reference(s)