Mov10l1^tm1.2Eno
Targeted Allele Detail

Summary

• Symbol: Mov10l1^tm1.2Eno
• Name: Mov10 like RISC complex RNA helicase 1; targeted mutation 1.2, Eric N Olson
• MGI ID: MGI:4457261
• Gene: Mov10l1 Location: Chr15:88867112-88939355 bp, + strand Genetic Position: Chr15, 44.49 cM
• Alliance: Mov10l1^tm1.2Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161124
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed exon 20. This allele produces a protein product that lacks the helicase domain. (J:161124)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mov10l1 Mutation: 46 strains or lines available

References

• Original: J:161124 Frost RJ, et al., MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11847-52
• All: 3 reference(s)