Adipor1^tm2Tka
Targeted Allele Detail

Summary

• Symbol: Adipor1^tm2Tka
• Name: adiponectin receptor 1; targeted mutation 2, Takashi Kadowaki
• MGI ID: MGI:4457490
• Gene: Adipor1 Location: Chr1:134343116-134361089 bp, + strand Genetic Position: Chr1, 58.22 cM, cytoband E4
• Alliance: Adipor1^tm2Tka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159462
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A loxP site was inserted into intron 2 and a floxed neo cassette was inserted into intron 5. (J:159462)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adipor1 Mutation: 45 strains or lines available

References

• Original: J:159462 Iwabu M, et al., Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1. Nature. 2010 Apr 29;464(7293):1313-9
• All: 1 reference(s)