Ehd1^tm1.1Haba
Targeted Allele Detail

Summary

• Symbol: Ehd1^tm1.1Haba
• Name: EH-domain containing 1; targeted mutation 1.1, Hamid Band
• MGI ID: MGI:4458097
• Synonyms: Ehd1^fl-Neo
• Gene: Ehd1 Location: Chr19:6326926-6350126 bp, + strand Genetic Position: Chr19, 4.4 cM
• Alliance: Ehd1^tm1.1Haba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160452
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: Two loxP sites were introduced to flank exon 1 by recombineering. An engineered FRT-Neo-FRT selection cassette was immediately preceding the second loxP site. The FRT-flanked Neo gene was deleted by FLPe-mediated recombination. (J:160452)

Generation of the Ehd1^tm1.2Haba and Ehd1^tm1.1Haba alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ehd1 Mutation: 40 strains or lines available

References

• Original: J:160452 Rainey MA, et al., The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice. BMC Dev Biol. 2010;10:37
• All: 2 reference(s)