Ccr7^Gt(hpk)Byg
Gene trapped Allele Detail

Summary

• Symbol: Ccr7^Gt(hpk)Byg
• Name: C-C motif chemokine receptor 7; gene trap hpk, BayGenomics
• MGI ID: MGI:4458322
• Gene: Ccr7 Location: Chr11:99035025-99045903 bp, - strand Genetic Position: Chr11, 62.92 cM, cytoband D
• Alliance: Ccr7^Gt(hpk)Byg page

Mutation origin

• Mutant Cell Line: hpk
• Germline Transmission: Earliest citation of germline transmission: J:161269
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1.8geo
• Mutation details: The beta-geo containing gene trap vector inserted into the 5'UTR. Expression of beta-galactosidase was detected in the hippocampal CA1 region and cortex. (J:161269)

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
Loading...
hm1	Ccr7^Gt(hpk)Byg/Ccr7^Gt(hpk)Byg	involves: 129 * C57BL/6

Phenotypes:

Affected Systems	hm1
show or hide all annotated terms
nervous system	√
nervous system phenotype	N
enhanced long-term potentiation	√

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr7 Mutation: 29 strains or lines available

References

• Original: J:161269 Steel M, et al., Gene-trapping to identify and analyze genes expressed in the mouse hippocampus. Hippocampus. 1998;8(5):444-57
• All: 1 reference(s)