Myo6^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Myo6^M1Btlr
• Name: myosin VI; mutation 1, Bruce Beutler
• MGI ID: MGI:4458386
• Synonyms: mayday circler
• Gene: Myo6 Location: Chr9:80072313-80219011 bp, + strand Genetic Position: Chr9, 43.98 cM
• Alliance: Myo6^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation comprises a T to A transversion at nucleotide position 929 of the mRNA sequence, in the ninth of the gene's 33 exons. It converts a triplet encoding cysteine at amino acid position 236 of the 1262-amino acid myosin VI protein to a premature termination codon (C236Ter). (J:86521, J:161348)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo6 Mutation: 91 strains or lines available

References

• Original: J:161348 Won S, et al., Record for mayday circler, updated 1 July 2010. MGI Direct Data Submission. 2010
• All: 3 reference(s)