Ntsr2^tm1Dafe
Targeted Allele Detail

Summary

• Symbol: Ntsr2^tm1Dafe
• Name: neurotensin receptor 2; targeted mutation 1, David Feifel
• MGI ID: MGI:4459069
• Synonyms: NT2^-
• Gene: Ntsr2 Location: Chr12:16703477-16710223 bp, + strand Genetic Position: Chr12, 7.98 cM
• Alliance: Ntsr2^tm1Dafe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160157
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis. (J:160157)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntsr2 Mutation: 22 strains or lines available

References

• Original: J:160157 Feifel D, et al., Effects of neurotensin-2 receptor deletion on sensorimotor gating and locomotor activity. Behav Brain Res. 2010 Oct 15;212(2):174-178
• All: 1 reference(s)