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Pals1tm1Caw
Targeted Allele Detail
Summary
Symbol: Pals1tm1Caw
Name: protein associated with LIN7 1, MAGUK family member; targeted mutation 1, Christopher A Walsh
MGI ID: MGI:4459078
Synonyms: Pals1f
Gene: Pals1  Location: Chr12:78795681-78887488 bp, + strand  Genetic Position: Chr12, 35.51 cM
Alliance: Pals1tm1Caw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:160624
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upsteam of exon 3 and an additional loxP site was inserted downstream of exon 3. (J:160624)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 11 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pals1 Mutation:  36 strains or lines available
References
Original:  J:160624 Kim S, et al., The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 2010 Apr 15;66(1):69-84
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory