Tpbg^tm1Plst
Targeted Allele Detail

Summary

• Symbol: Tpbg^tm1Plst
• Name: trophoblast glycoprotein; targeted mutation 1, Peter L Stern
• MGI ID: MGI:4459319
• Synonyms: 5T4^-
• Gene: Tpbg Location: Chr9:85724433-85729093 bp, + strand Genetic Position: Chr9, 46.4 cM
• Alliance: Tpbg^tm1Plst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160174
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The single coding exon 2 was replaced with an IRES-LacZneo cassette. (J:160174)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tpbg Mutation: 24 strains or lines available

References

• Original: J:160174 Southgate TD, et al., CXCR4 mediated chemotaxis is regulated by 5T4 oncofetal glycoprotein in mouse embryonic cells. PLoS One. 2010;5(4):e9982
• All: 6 reference(s)