Tg(Tek-cre)#Xya
Transgene Detail

Summary

• Symbol: Tg(Tek-cre)#Xya
• Name: transgene insertion, Xiao Yang
• MGI ID: MGI:4459419
• Synonyms: Tie2-Cre
• Transgene: Tg(Tek-cre)#Xya Location: unknown
• Alliance: Tg(Tek-cre)#Xya page

Transgene origin

• Strain of Origin: Kunming

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tek-cre)#Xya expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tek (MGI:98664)

• Mutation details: The transgene construct consisted of the 2.1 kb murine Tek (Tie2) promoter fragment and a 10.5 kb fragment of exon 1 containing an enhancer sequence ligated to the cre cDNA and hGH polyA signal sequence. This linearized construct (15.9 kb) was microinjected into pronuclei of fertilized Kunming oocytes. 6 transgenic founders were obtained; however, no line numbers were specified for founders. (J:161504)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tek (mouse) Summary of all recombinase alleles driven by Tek. Comparative matrix view of recombinase activities Alliance mouse Tek gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:161504 Li WL, et al., Endothelial cell-specific expression of Cre recombinase in transgenic mice. Yi Chuan Xue Bao. 2005 Sep;32(9):909-15
• All: 10 reference(s)