Pknox1^tm1Ngc
Targeted Allele Detail

Summary

• Symbol: Pknox1^tm1Ngc
• Name: Pbx/knotted 1 homeobox; targeted mutation 1, Neal G Copeland
• MGI ID: MGI:4459452
• Gene: Pknox1 Location: Chr17:31783708-31826667 bp, + strand Genetic Position: Chr17, 16.78 cM, cytoband B-C
• Alliance: Pknox1^tm1Ngc page

Pro-B tumor in Pknox1^tm1Ngc/Pknox1⁺ Tg(IghMyc)22Bri/0 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111418
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• No molecular information is reported.

Expression

In Mice Carrying this Mutation:

13 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pknox1 Mutation: 90 strains or lines available

References

• Original: J:111418 Ferretti E, et al., Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol Cell Biol. 2006 Aug;26(15):5650-62
• All: 4 reference(s)