Timd4^tm1Wouy
Targeted Allele Detail

Summary

• Symbol: Timd4^tm1Wouy
• Name: T cell immunoglobulin and mucin domain containing 4; targeted mutation 1, Wenjun Ouyang
• MGI ID: MGI:4459454
• Synonyms: Tim-4^-
• Gene: Timd4 Location: Chr11:46701627-46735159 bp, + strand Genetic Position: Chr11, 28.09 cM
• Alliance: Timd4^tm1Wouy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160304
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exons 2 and 3 were replaced with a neo cassette. The absence of protein expression was confirmed by FACS analysis on cells from the peritoneal cavity. (J:160304)

Generation of the Timd4^tm1Wouy allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Timd4 Mutation: 29 strains or lines available

References

• Original: J:160304 Wong K, et al., Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8712-7
• All: 5 reference(s)