Il17rc^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Il17rc^tm1Lex
• Name: interleukin 17 receptor C; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:4459513
• Gene: Il17rc Location: Chr6:113448416-113460124 bp, + strand Genetic Position: Chr6, 52.77 cM, cytoband E3
• Alliance: Il17rc^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161073
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1-5 encompassing the Il17rc coding sequence were replaced with a LacZ neomycin resistance cassette. (J:161073)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Il17rc Mutation: 34 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:161073 Zheng Y, et al., Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med. 2008 Mar;14(3):282-9
• All: 18 reference(s)