Kif26b^tm1.1Ryn
Targeted Allele Detail

Summary

• Symbol: Kif26b^tm1.1Ryn
• Name: kinesin family member 26B; targeted mutation 1.1, Ryuichi Nishinakamura
• MGI ID: MGI:4459557
• Gene: Kif26b Location: Chr1:178356690-178766765 bp, + strand Genetic Position: Chr1, 83.16 cM, cytoband H3
• Alliance: Kif26b^tm1.1Ryn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160285
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Intron 6 was replaced with a lacZ cassette with a 5' loxP site and a 3' polyadenylation sequence, an frt flanked neo cassette, and a 3' loxP site. Flp mediated recombination removed the neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:160285)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif26b Mutation: 81 strains or lines available

References

• Original: J:160285 Uchiyama Y, et al., Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9240-5
• All: 2 reference(s)