Clec4n^tm1Yiw
Targeted Allele Detail

Summary

• Symbol: Clec4n^tm1Yiw
• Name: C-type lectin domain family 4, member n; targeted mutation 1, Yoichiro Iwakura
• MGI ID: MGI:4459637
• Synonyms: Dectin-2^-
• Gene: Clec4n Location: Chr6:123206802-123223980 bp, + strand Genetic Position: Chr6, 58.3 cM, cytoband F3
• Alliance: Clec4n^tm1Yiw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160680
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1 and 2 were replaced by a neomycin-resistance cassette. (J:160680)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec4n Mutation: 27 strains or lines available

References

• Original: J:160680 Saijo S, et al., Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. Immunity. 2010 May 28;32(5):681-91
• All: 38 reference(s)