Fpr2^tm1.1Jimw
Targeted Allele Detail

Summary

• Symbol: Fpr2^tm1.1Jimw
• Name: formyl peptide receptor 2; targeted mutation 1.1, Ji Ming Wang
• MGI ID: MGI:4459724
• Synonyms: mFPR2^neoloxp
• Gene: Fpr2 Location: Chr17:18108086-18114214 bp, + strand Genetic Position: Chr17, 10.66 cM, cytoband A3.1
• Alliance: Fpr2^tm1.1Jimw page

Decreased colon crypt length in Fpr2^tm1.1Jimw/Fpr2^tm1.1Jimw Tg(Vil1-cre)997Gum/0 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160074
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of the coding exon and an additional loxP site was inserted downstream of the coding exon. Cre mediated recombination removes the neo cassette leaving the coding exon floxed. (J:160074)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fpr2 Mutation: 24 strains or lines available

References

• Original: J:160074 Chen K, et al., A critical role for the g protein-coupled receptor mFPR2 in airway inflammation and immune responses. J Immunol. 2010 Apr 1;184(7):3331-5
• All: 4 reference(s)