Fpr2^tm1.2Jimw
Targeted Allele Detail

Summary

• Symbol: Fpr2^tm1.2Jimw
• Name: formyl peptide receptor 2; targeted mutation 1.2, Ji Ming Wang
• MGI ID: MGI:4459725
• Synonyms: mFPR2^-
• Gene: Fpr2 Location: Chr17:18108086-18114214 bp, + strand Genetic Position: Chr17, 10.66 cM, cytoband A3.1
• Alliance: Fpr2^tm1.2Jimw page

Reduced length of colonic crypts in Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw and Del(17Fpr1-Fpr2)1Jimw/Del(17Fpr1-Fpr2)1Jimw mice

Show the 7 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160074
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed the neo cassette and coding exon. The absence of transcript expression was confirmed by RT-PCR on bone marrow cell extract. (J:160074)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fpr2 Mutation: 24 strains or lines available

References

• Original: J:160074 Chen K, et al., A critical role for the g protein-coupled receptor mFPR2 in airway inflammation and immune responses. J Immunol. 2010 Apr 1;184(7):3331-5
• All: 25 reference(s)