Gimap1^tm1.1Gwb
Targeted Allele Detail

Summary

• Symbol: Gimap1^tm1.1Gwb
• Name: GTPase, IMAP family member 1; targeted mutation 1.1, Geoffrey W Butcher
• MGI ID: MGI:4459837
• Gene: Gimap1 Location: Chr6:48715988-48720729 bp, + strand Genetic Position: Chr6, 23.69 cM, cytoband B
• Alliance: Gimap1^tm1.1Gwb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160782
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 3 was flanked by loxP sites and 3' of that a neomycin-resistance cassette was located between FRT sites. The selection cassette was removed by flp mediated recombination. (J:160782)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gimap1 Mutation: 8 strains or lines available

References

• Original: J:160782 Saunders A, et al., Putative GTPase GIMAP1 is critical for the development of mature B and T lymphocytes. Blood. 2010 Apr 22;115(16):3249-57
• All: 3 reference(s)