Ace3^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Ace3^tm1Osb
• Name: angiotensin I converting enzyme 3; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:4459895
• Gene: Ace3 Location: Chr11:105885501-105896269 bp, + strand Genetic Position: Chr11, 68.86 cM
• Alliance: Ace3^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160139
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: The first 9 exons were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on sperm extracts. (J:160139)

Generation of the Ace3^tm1Osb allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ace3 Mutation: 22 strains or lines available

References

• Original: J:160139 Inoue N, et al., Identification and disruption of sperm-specific angiotensin converting enzyme-3 (ACE3) in mouse. PLoS One. 2010;5(4):e10301
• All: 2 reference(s)