Adcy6^tm1Yich
Targeted Allele Detail

Summary

• Symbol: Adcy6^tm1Yich
• Name: adenylate cyclase 6; targeted mutation 1, Yijuang Chern
• MGI ID: MGI:4459915
• Gene: Adcy6 Location: Chr15:98487854-98507957 bp, - strand Genetic Position: Chr15, 54.59 cM, cytoband F
• Alliance: Adcy6^tm1Yich page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161317
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a gfp-neo cassette by homologous recombination. Absence of protein was confirmed by western blot and GFP expression was observed. (J:161317)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adcy6 Mutation: 50 strains or lines available

References

• Original: J:161317 Chien CL, et al., Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6). FEBS Lett. 2010 Jul 2;584(13):2883-90
• All: 3 reference(s)