C1qtnf5^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: C1qtnf5^{tm1(KOMP)Vlcg}
• Name: C1q and tumor necrosis factor related protein 5; targeted mutation 1, Velocigene
• MGI ID: MGI:4460570
• Synonyms: Ctrp5 KO
• Gene: C1qtnf5 Location: Chr9:44018542-44020484 bp, + strand Genetic Position: Chr9, 24.62 cM
• Alliance: C1qtnf5^{tm1(KOMP)Vlcg} page
• IMPC: C1qtnf5 gene page

Mutation origin

• Mutant Cell Lines: 12534A-D8, 12534A-G8, 12534A-H4, 12534A-H11
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1090bp between positions 44019058-44020147 of Chromosome 9 (Build GRCm39). The entire gene, comprising two exons, was replaced by a neomycin resistance gene and lacZ reporter cassette. RT-PCR analysis confirmed the absence of mRNA transcripts in epididymal white adipose tissue from homozygous mutant mice. (J:136110, J:237401)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any C1qtnf5 Mutation: 14 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)