Srpk2^tm1Nik
Targeted Allele Detail

Summary

• Symbol: Srpk2^tm1Nik
• Name: serine/arginine-rich protein specific kinase 2; targeted mutation 1, Nigel Killeen
• MGI ID: MGI:4460670
• Gene: Srpk2 Location: Chr5:23708262-23889615 bp, - strand Genetic Position: Chr5, 10.36 cM
• Alliance: Srpk2^tm1Nik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161558
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A puro cassette, loxP site, and 3'Hprt minigene with IRES GFP were inserted into intron 14-15 duplicating part of the gene. (J:161558)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srpk2 Mutation: 47 strains or lines available

References

• Original: J:161558 Wong JC, et al., Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies. Blood. 2010 Jun 3;115(22):4524-32
• All: 1 reference(s)