Fastk^tm1.1Andp
Targeted Allele Detail

Summary

• Symbol: Fastk^tm1.1Andp
• Name: Fas-activated serine/threonine kinase; targeted mutation 1, Paul Anderson
• MGI ID: MGI:4461026
• Gene: Fastk Location: Chr5:24646036-24650280 bp, - strand Genetic Position: Chr5, 11.78 cM, cytoband A3
• Alliance: Fastk^tm1.1Andp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:160443
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence was replaced by a floxed neo cassette. The selection cassette was removed by cre mediated recombination. (J:160443)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fastk Mutation: 22 strains or lines available

References

• Original: J:160443 Simarro M, et al., Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation. J Immunol. 2010 May 1;184(9):5325-32
• All: 6 reference(s)