Sufu^tm1.1Blnw
Targeted Allele Detail

Summary

• Symbol: Sufu^tm1.1Blnw
• Name: SUFU negative regulator of hedgehog signaling; targeted mutation 1.1, Baolin Wang
• MGI ID: MGI:4461193
• Gene: Sufu Location: Chr19:46385335-46477243 bp, + strand Genetic Position: Chr19, 38.85 cM
• Alliance: Sufu^tm1.1Blnw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161408
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre mediated recombination removed the neo cassette and exon 1. (J:161408)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sufu Mutation: 59 strains or lines available

References

• Original: J:161408 Wang C, et al., Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development. 2010 Jun;137(12):2001-9
• All: 2 reference(s)