Ar^tm2Ska
Targeted Allele Detail

Summary

• Symbol: Ar^tm2Ska
• Name: androgen receptor; targeted mutation 2, Shigeaki Kato
• MGI ID: MGI:4461236
• Synonyms: AR^L2, Ar^lox
• Gene: Ar Location: ChrX:97192375-97366821 bp, + strand Genetic Position: ChrX, 42.82 cM
• Alliance: Ar^tm2Ska page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85484
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was introduced downstream. This allele was used to generate Ar^tm1Ska. (J:85484)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ar Mutation: 23 strains or lines available

References

• Original: J:85484 Matsumoto T, et al., Androgen receptor functions from reverse genetic models. J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):95-9
• All: 15 reference(s)