Hoxa3^tm3.1Nrm
Targeted Allele Detail

Summary

• Symbol: Hoxa3^tm3.1Nrm
• Name: homeobox A3; targeted mutation 3.1, Nancy R Manley
• MGI ID: MGI:4461308
• Synonyms: Hoxa3^fx
• Gene: Hoxa3 Location: Chr6:52146042-52190316 bp, - strand Genetic Position: Chr6, 25.4 cM
• Alliance: Hoxa3^tm3.1Nrm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161296
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The two protein coding exons were flanked with loxP sites and an FRT flanked neo cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:217502)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxa3 Mutation: 24 strains or lines available

References

• Original: J:161296 Chen L, et al., Mouse and zebrafish Hoxa3 orthologues have nonequivalent in vivo protein function. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10555-60
• All: 3 reference(s)