Ccna2^tm1.2Pisc
Targeted Allele Detail

Summary

• Symbol: Ccna2^tm1.2Pisc
• Name: cyclin A2; targeted mutation 1.2, Piotr Sicinski
• MGI ID: MGI:4461956
• Synonyms: A2^delta
• Gene: Ccna2 Location: Chr3:36619014-36626299 bp, - strand Genetic Position: Chr3, 17.67 cM
• Alliance: Ccna2^tm1.2Pisc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155178
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed the neo cassette and exons 2 through 7. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:155178)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccna2 Mutation: 15 strains or lines available

References

• Original: J:155178 Kalaszczynska I, et al., Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells. Cell. 2009 Jul 23;138(2):352-65
• All: 1 reference(s)