Sema6c^tm1Matl
Targeted Allele Detail

Summary

• Symbol: Sema6c^tm1Matl
• Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C; targeted mutation 1, Marc Tessier-Lavigne
• MGI ID: MGI:4461964
• Gene: Sema6c Location: Chr3:95067768-95081335 bp, + strand Genetic Position: Chr3, 40.74 cM, cytoband F2
• Alliance: Sema6c^tm1Matl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161856
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A secretory gene trap cassette was inserted into intron 15 by the targeted trapping method. Absence of wild-type transcript was confirmed by Northern blot analysis of brain mRNA from 4 day old pups. (J:161856)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema6c Mutation: 43 strains or lines available

References

• Original: J:161856 Takamatsu H, et al., Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol. 2010 Jul;11(7):594-600
• All: 5 reference(s)