Sema6d^tm1Kik
Targeted Allele Detail

Summary

• Symbol: Sema6d^tm1Kik
• Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; targeted mutation 1, Hitoshi Kikutani
• MGI ID: MGI:4461971
• Gene: Sema6d Location: Chr2:123931889-124509690 bp, + strand Genetic Position: Chr2, 60.69 cM
• Alliance: Sema6d^tm1Kik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161856
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 0.6 kbp fragment containing exon 2 in which the initiation codon is found as well as exon3 was replaced by a neomycin resistance cassette. (J:161856)

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema6d Mutation: 62 strains or lines available

References

• Original: J:161856 Takamatsu H, et al., Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol. 2010 Jul;11(7):594-600
• All: 7 reference(s)