Tg(Cd8a*-cre)B8Asin
Transgene Detail

Summary

• Symbol: Tg(Cd8a*-cre)B8Asin
• Name: transgene insertion B8, Alfred Singer
• MGI ID: MGI:4462361
• Synonyms: E8III-Cre
• Transgene: Tg(Cd8a*-cre)B8Asin Location: unknown
• Alliance: Tg(Cd8a*-cre)B8Asin page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Cd8a*-cre)B8Asin expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Cd8a

• Mutation details: A transgene was constructed with the E8_III enhancer and promoter elements from Cd8a driving expression of cre recombinase in SP and DP thymocytes. (J:158504)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cd8a (species not specified) Summary of all recombinase alleles driven by Cd8a.

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:158504 Park JH, et al., Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells. Nat Immunol. 2010 Mar;11(3):257-64
• All: 10 reference(s)