Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi
Transgene Detail

Summary

• Symbol: Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi
• Name: transgene insertion, Hirotake Ichise
• MGI ID: MGI:4462365
• Synonyms: CGH tg
• Transgene: Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi Location: unknown
• Alliance: Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:159024
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hras (MGI:96224)

• Mutation details: An Hras1-IRES-EGFP cDNA cassette was cloned into a vector containing the CAGGs promoter followed by a loxP-flanked Beta-geo cassette. The transgenic vector was introduced into E14.1 ES cells. Transgene expressing ES cells were selected and injected into C57BL/6 blastocysts that were transplanted into MCH:ICR female mice. No line numbers for founders were specified. (J:159024)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:159024 Ichise T, et al., H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice. Development. 2010 Mar;137(6):1003-13
• All: 3 reference(s)