Inpp4a^tm1Tsak
Targeted Allele Detail

Summary

• Symbol: Inpp4a^tm1Tsak
• Name: inositol polyphosphate-4-phosphatase, type I; targeted mutation 1, Takehiko Sasaki
• MGI ID: MGI:4462378
• Synonyms: Inpp4a^deltaEx1,2
• Gene: Inpp4a Location: Chr1:37338946-37449817 bp, + strand Genetic Position: Chr1, 15.46 cM
• Alliance: Inpp4a^tm1Tsak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161963
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The first and second coding exons were replaced with a LacZ-neo cassette. (J:161963)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Inpp4a Mutation: 55 strains or lines available

References

• Original: J:161963 Sasaki J, et al., The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death. Nature. 2010 May 27;465(7297):497-501
• All: 2 reference(s)