Sall1^tm1.1Mrau
Targeted Allele Detail

Summary

• Symbol: Sall1^tm1.1Mrau
• Name: spalt like transcription factor 1; targeted mutation 1.1, Michael Rauchman
• MGI ID: MGI:4462422
• Synonyms: Sall1-deltaZn-Cre
• Gene: Sall1 Location: Chr8:89753867-89770790 bp, - strand Genetic Position: Chr8, 43.51 cM, cytoband D
• Alliance: Sall1^tm1.1Mrau page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161758
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated from Sall1^tm1Mrau by crossing with cre deleter mice to remove a floxed neo casset after inserted stop codon into the exon 2. The deleted region corresponded with nt 1300-3443 of the cDNA. (J:161758)
• Inheritance: Dominant

Disease models

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall1 Mutation: 78 strains or lines available

References

• Original: J:161758 Kiefer SM, et al., SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes. Hum Mutat. 2008 Sep;29(9):1133-40
• All: 1 reference(s)