Tg(Trh-cre)5Anh
Transgene Detail

Summary

• Symbol: Tg(Trh-cre)5Anh
• Name: transgene insertion 5, Anthony Hollenberg
• MGI ID: MGI:4462700
• Synonyms: F5:TRH-Cre
• Transgene: Tg(Trh-cre)5Anh Location: unknown
• Alliance: Tg(Trh-cre)5Anh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Trh-cre)5Anh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Trh

• Mutation details: The cDNA encoding cre recombinase was inserted downstream of the endogenous ATG codon in exon 2 of the Trh gene in a BAC containing the entire Trh gene and at least 30 kb and 40 kb of 5' and 3' flanking sequences respectively. The purified vector was used to generate transgenic lines. Two founder lines, 5 and 40, were subsequently analyzed. (J:162058)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Trh (species not specified) Summary of all recombinase alleles driven by Trh. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:162058 Sugrue ML, et al., The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo. Endocrinology. 2010 Feb;151(2):793-801
• All: 2 reference(s)