Ppib^tm1Rjb
Targeted Allele Detail

Summary

• Symbol: Ppib^tm1Rjb
• Name: peptidylprolyl isomerase B; targeted mutation 1, Richard J Bram
• MGI ID: MGI:4462801
• Gene: Ppib Location: Chr9:65967504-65973905 bp, + strand Genetic Position: Chr9, 35.69 cM
• Alliance: Ppib^tm1Rjb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161748
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP and frt franked neo was inserted into the intron between exon 2 and 3, and another lox P site was inserted into intron after exon 3. This is a conditional null allele. (J:161748)

Generation of the Ppib^tm1Rjb and Ppib^tm1.1Rjb alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppib Mutation: 18 strains or lines available

References

• Original: J:161748 Choi JW, et al., Severe osteogenesis imperfecta in cyclophilin B-deficient mice. PLoS Genet. 2009 Dec;5(12):e1000750
• All: 1 reference(s)