Tg(Ins1-SLC2A1)1Thor
Transgene Detail

Summary

• Symbol: Tg(Ins1-SLC2A1)1Thor
• Name: transgene insertion 1, Bernard Thorens
• MGI ID: MGI:4462831
• Synonyms: RIPG1, ripglut1
• Transgene: Tg(Ins1-SLC2A1)1Thor Location: unknown
• Alliance: Tg(Ins1-SLC2A1)1Thor page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins1-SLC2A1)1Thor expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SLC2A1 (6513)

  Slc2a1

  (MGI:95755)

• Mutation details: A 3.1 kb transgenic vector containg the SLC2A1 (GLUT1) cDNA under control of the rat insulin promoter I was injected into C57BL/6 oocytes. (J:63850)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:63850 Thorens B, et al., Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion. J Biol Chem. 2000 Aug 4;275(31):23751-8
• All: 9 reference(s)