About   Help   FAQ
Gt(ROSA)26Sortm1.1(Sall1)Ryn
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1.1(Sall1)Ryn
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Ryuichi Nishinakamura
MGI ID: MGI:4462841
Synonyms: Gt(ROSA)26Sortm1.1(Sall1)Ryni
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1.1(Sall1)Ryn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162052
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1.1(Sall1)Ryn expresses 1 gene
 
Mutation detailsA floxed neo cassette and tpA Stop sequence followed by an HA-tagged Sall1 ORF were inserted into the ROSA26 locus by homologous recombination such that removal of the tpA stop sequence within the floxed neo cassette would allow transcription of the Sall1 gene. The Neo and STOP were removed by cre mediated recombination. (J:162052)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
References
Original:  J:162052 Jiang Q, et al., Overexpression of Sall1 in vivo leads to reduced body weight without affecting kidney development. J Biochem. 2010 Mar;147(3):445-50
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory