Ssbp2^tm1Lana
Targeted Allele Detail

Summary

• Symbol: Ssbp2^tm1Lana
• Name: single-stranded DNA binding protein 2; targeted mutation 1, Lalitha Nagarajan
• MGI ID: MGI:4462848
• Gene: Ssbp2 Location: Chr13:91608402-91851548 bp, + strand Genetic Position: Chr13, 47.43 cM
• Alliance: Ssbp2^tm1Lana page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162035
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on thymus extracts. (J:162035)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ssbp2 Mutation: 38 strains or lines available

References

• Original: J:162035 Wang Y, et al., SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability. Oncogene. 2010 May 27;29(21):3044-53
• All: 2 reference(s)