Fgf22^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Fgf22^tm1Dgen
• Name: fibroblast growth factor 22; targeted mutation 1, Deltagen
• MGI ID: MGI:4818348
• Gene: Fgf22 Location: Chr10:79590887-79593629 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Fgf22^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161954
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and a part of exon 2 was replaced with the neomycin-resistant gene. The absence of transcript expression was confirmed by in situ hybridization. (J:161954)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf22 Mutation: 15 strains or lines available

References

• Original: J:161954 Terauchi A, et al., Distinct FGFs promote differentiation of excitatory and inhibitory synapses. Nature. 2010 Jun 10;465(7299):783-7
• All: 7 reference(s)