Gja5tm1Mchn
Targeted Allele Detail
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Symbol: |
Gja5tm1Mchn |
Name: |
gap junction protein, alpha 5; targeted mutation 1, Marc Chanson |
MGI ID: |
MGI:4818408 |
Synonyms: |
Cx40fl, Gja5flox |
Gene: |
Gja5 Location: Chr3:96939718-96960950 bp, + strand Genetic Position: Chr3, 42.04 cM
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Alliance: |
Gja5tm1Mchn page
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Germline Transmission: |
Earliest citation of germline transmission:
J:162224
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A floxed neo cassette was inserted upstream of exon 2, and a loxP site was inserted downstream of exon 2. The loxP-neomycin-loxP cassette was excised from the targeted ES cells by transient in vitro expression of cre recombinase, leaving exon 2 flanked by loxP sites.
(J:162224)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gja5 Mutation: |
18 strains or lines available
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Original: |
J:162224 Chadjichristos CE, et al., Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion. Circulation. 2010 Jan 5;121(1):123-31 |
All: |
6 reference(s) |
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