Pik3r1^tm2Dfr
Targeted Allele Detail

Summary

• Symbol: Pik3r1^tm2Dfr
• Name: phosphoinositide-3-kinase regulatory subunit 1; targeted mutation 2, David A Fruman
• MGI ID: MGI:4818438
• Synonyms: Pik3r1^tm2Dfi
• Gene: Pik3r1 Location: Chr13:101817269-101904725 bp, - strand Genetic Position: Chr13, 53.92 cM
• Alliance: Pik3r1^tm2Dfr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This mutation substitutes a neomycin resistance cassette for exon 7, the first exon common to the three alternative transcripts encoding the p85alpha, p55alpha and p50alpha regulatory subunits, and some flanking intronic DNA. (J:94077)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pik3r1 Mutation: 56 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)