Tg(APOE-SGMS2)#Jia
Transgene Detail

Summary

• Symbol: Tg(APOE-SGMS2)#Jia
• Name: transgene insertion, Xian-Cheng Jiang
• MGI ID: MGI:4818467
• Synonyms: SMS2Tg
• Transgene: Tg(APOE-SGMS2)#Jia Location: unknown
• Alliance: Tg(APOE-SGMS2)#Jia page

Transgene origin

• Strain of Origin: C57BL/6 and CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOE-SGMS2)#Jia expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SGMS2 (166929)

  Sgms2

  (MGI:1921692)

• Mutation details: The human APOE promoter with exon 1, intron 1, and exon 2 drives liver-specific expression of the human cDNA followed by the APOE liver element. No line number was given (denoted by #). (J:162192)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:162192 Liu J, et al., Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice. Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):850-6
• All: 1 reference(s)