Gata2^tm1Msal
Targeted Allele Detail

Summary

• Symbol: Gata2^tm1Msal
• Name: GATA binding protein 2; targeted mutation 1, Marjo Salminen
• MGI ID: MGI:4818492
• Synonyms: Gata2^c, Gata2^flox
• Gene: Gata2 Location: Chr6:88170873-88184014 bp, + strand Genetic Position: Chr6, 39.2 cM
• Alliance: Gata2^tm1Msal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143527
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1G and a floxed neo cassette was inserted downstream of exon 3 via homologous recombination. (J:143527, J:163272)

Expression

In Mice Carrying this Mutation:

16 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gata2 Mutation: 30 strains or lines available

References

• Original: J:143527 Kala K, et al., Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons. Development. 2009 Jan;136(2):253-62
• All: 14 reference(s)