Ext1^tm1.1Yama
Targeted Allele Detail

Summary

• Symbol: Ext1^tm1.1Yama
• Name: exostosin glycosyltransferase 1; targeted mutation 1.1, Yu Yamaguchi
• MGI ID: MGI:4818621
• Gene: Ext1 Location: Chr15:52931657-53209579 bp, - strand Genetic Position: Chr15, 20.0 cM
• Alliance: Ext1^tm1.1Yama page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161395
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre mediated recombination removed exon 1. (J:161395)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ext1 Mutation: 65 strains or lines available

References

• Original: J:161395 Matsumoto K, et al., A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10932-7
• All: 2 reference(s)