Ucn2^tm1.1Jde
Targeted Allele Detail

Summary

• Symbol: Ucn2^tm1.1Jde
• Name: urocortin 2; targeted mutation 1.1, Jan Deussing
• MGI ID: MGI:4818656
• Synonyms: Ucn2^tZ
• Gene: Ucn2 Location: Chr9:108815231-108816232 bp, + strand Genetic Position: Chr9, 59.63 cM, cytoband F2
• Alliance: Ucn2^tm1.1Jde page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161776
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire open reading frame was replaced with a tau-lacZ reporter and a self-excising neo cassette via homologous recombination. (J:161776)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ucn2 Mutation: 8 strains or lines available

References

• Original: J:161776 Deussing JM, et al., Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2. J Neurosci. 2010 Jul 7;30(27):9103-16
• All: 2 reference(s)