Bcl11b^tm1Peli
Targeted Allele Detail

Summary

• Symbol: Bcl11b^tm1Peli
• Name: B cell leukemia/lymphoma 11B; targeted mutation 1, Pentao Liu
• MGI ID: MGI:4818771
• Synonyms: Bcl11b^flox
• Gene: Bcl11b Location: Chr12:107876662-107969861 bp, - strand Genetic Position: Chr12, 59.1 cM, cytoband F1
• Alliance: Bcl11b^tm1Peli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:161373
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 4. (J:161373)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl11b Mutation: 46 strains or lines available

References

• Original: J:161373 Li P, et al., Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science. 2010 Jul 2;329(5987):85-9
• All: 11 reference(s)